Zuppi received the cardinal’s red hat in October 2019 and emphasized the importance of connection over individualism in his homily during the ceremony. His strong ties with the Roman community also earn him the affectionate nickname "Don Matteo," reminiscent of a popular fictional priest-character. As speculation around the conclave continues to grow, Zuppi’s commitment to social causes and conflict resolution positions him as a suitable candidate to lead the Catholic Church into the future.

In his public engagements, Zuppi shows a profound understanding of the struggles faced by the poor and disenfranchised populations, which has caught the attention of Vatican analysts who are monitoring potential successors to Pope Francis. Many believe that if elected, he could carry forth the current Pope's initiatives aimed at promoting peace and social justice across the globe. With increasing discussions around papal succession, Cardinal Zuppi's name is likely to remain in the spotlight as the Church navigates its next chapter.