An Iranian missile strike has hit the town of Dimona in southern Israel, near to a nuclear facility.

The International Atomic Energy Agency (IAEA) said it was not aware of any damage to the nuclear research facility located about eight miles (13km) outside Dimona.

Iranian state TV said the strike was in response to a reported attack on Iran's Natanz nuclear facility earlier on Saturday. The IAEA said no increase in off-site radiation levels had been reported after that incident.

Rafael Grossi, the IAEA's director general, said maximum military restraint should be observed, in particular in the vicinity of nuclear facilities.

Israel's ambulance service said it was treating 40 people following the strike in Dimona, including 37 with mild injuries and a 10-year-old boy in serious condition.

It said 68 others were being treated following a separate strike in the nearby town of Arad, including 47 with mild injuries and 10 in serious condition.

Emergency medical technician Yakir Talkar described the situation in Arad as a very severe scene, noting many wounded with varying degrees of injury.

Israeli authorities are now investigating how missiles made it through air defense systems.

Israeli firefighters reported that in both Dimona and Arad, interceptors were launched but failed to hit the threats, resulting in direct hits by ballistic missiles.

The Shimon Peres Negev Nuclear Research Center, known colloquially as the Dimona reactor, is acknowledged to hold Israel's undeclared arsenal of nuclear weapons, making any threat to it a serious concern for the Israeli government.

Both Israel and the US have prioritized eliminating any Iranian capacity to develop nuclear weapons as a key military objective.

Iran's Atomic Energy Organisation described the Natanz attack as a violation of the Treaty on the Non-Proliferation of Nuclear Weapons, while reporting no leakage of radioactive materials.

Both nations have witnessed increased military action since the onset of conflicts and airstrikes in February, which are ongoing amid heightened tensions in the region.